Western Molecular Targets

• 
• 

Chem-TCM lists predicted activities for each molecular record covering 41 therapeutically significant targets in Western medicine:

Nicotinic ACh antagonist

GABA antagonist

Na,K-ATPase

Voltage-gated Na channel

Adenosine receptor

Muscarinic ACh antagonist

alpha 1 Adrenergic receptor

alpha 2 Adrenergic receptor

beta Adrenergic receptor

Dopamine receptor

Acetylcholinesterase

MAO

Prolyl endopeptidase

cAMP phosphodiesterase

iNOS expression

NO prod'n in vivo

Calcium-dependent PK (CDPK)

Myosin light chain kinase (MLCK)

cAMP-dependent kinase (PKA)

Calcium-activated protein kinase (PKC)

Aldose reductase

Protein synthesis

DNA ligands

DNA polymerase

Topoisomerase I

Topoisomerase II

Apoptotic

HIV-1 integrase

HIV-1 protease

HIV-1 RT

Estrogen receptor

Estrogen aromatase

Angiotensin converting enzyme (ACE)

Electron transport chain (ETC)

Multidrug resistance transporter (MDR-TR)

Xanthine oxidase

COX (general)

LOX (general)

5-LOX

Phospholipase A2

Free radical scavengers/antioxidants